Empty Sella Syndrome

02 November 2015

Webinar Description

When the pituitary gland shrinks or becomes flattened, it cannot be seen on an MRI, making the pituitary gland look like an “empty sella.” The appearance of this term in radiology reports can cause anxiety for patients or confusion for providers who are not familiar with pituitary biology. In this webinar, Dr. Aghi will discuss what tissue can actually be found in a true “empty sella;” what causes an empty sella; and what, if anything, needs to be done about an empty sella.

Presenter Bio

Dr. Manish Aghi is a neurosurgeon specializing in the treatment of pituitary adenomas and other tumors of the anterior skull base by minimally invasive endonasal approaches. He has an MD and PhD from Harvard Medical School in Boston and did his neurosurgery residency at the Harvard affiliated Massachusetts General Hospital (MGH). Since joining UCSF six years ago, he has performed nearly 500 endonasal operations for pituitary tumors and, as the leader of an active clinical research program, he has published 24 articles on surgical technique and outcomes for pituitary tumor patients. He is currently directing a national effort sponsored by the Congress of Neurological Surgeons to establish evidence-based guidelines for neurosurgeons caring for patients with pituitary tumors.

Dr. Aghi also runs an NIH funded basic science laboratory investigating the molecules that allow pituitary tumors to grow and invade, and he is working with industry collaborators to develop molecular inhibitors that may someday be of benefit to prevent these processes. He is principal investigator of a pair of phase I/II clinical trials of experimental treatments for malignant brain tumors.

  • Dr. Manish Aghi
    Associate Professor in Residence of Neurological Surgery
    Principal Investigator, BTRC
    Maydan Family Endowed Faculty
    Attending Neurosurgeon, California Center for Pituitary Disorders
    Co-Director, Center for Minimally Invasive Skull Base Surgery
    Faculty Member, UCSF Graduate Division in Biomedical Sciences

Description

Webinar Description

When the pituitary gland shrinks or becomes flattened, it cannot be seen on an MRI, making the pituitary gland look like an “empty sella.” The appearance of this term in radiology reports can cause anxiety for patients or confusion for providers who are not familiar with pituitary biology. In this webinar, Dr. Aghi will discuss what tissue can actually be found in a true “empty sella;” what causes an empty sella; and what, if anything, needs to be done about an empty sella.

Presenter Bio

Dr. Manish Aghi is a neurosurgeon specializing in the treatment of pituitary adenomas and other tumors of the anterior skull base by minimally invasive endonasal approaches. He has an MD and PhD from Harvard Medical School in Boston and did his neurosurgery residency at the Harvard affiliated Massachusetts General Hospital (MGH). Since joining UCSF six years ago, he has performed nearly 500 endonasal operations for pituitary tumors and, as the leader of an active clinical research program, he has published 24 articles on surgical technique and outcomes for pituitary tumor patients. He is currently directing a national effort sponsored by the Congress of Neurological Surgeons to establish evidence-based guidelines for neurosurgeons caring for patients with pituitary tumors.

Dr. Aghi also runs an NIH funded basic science laboratory investigating the molecules that allow pituitary tumors to grow and invade, and he is working with industry collaborators to develop molecular inhibitors that may someday be of benefit to prevent these processes. He is principal investigator of a pair of phase I/II clinical trials of experimental treatments for malignant brain tumors.

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