December 2016 Pituitary Research Articles

Knowledge is power and we believe keeping abreast of news on the research front is imperative. Each month in Highlights we feature a few of the top news stories, which you can read below. In addition, we update our website on a regular basis with the latest breaking news related to pituitary and hormonal disorders by gathering stories we think you'll be interested in from MD Linx, Medscape, MedPage Today, PubMed, Touch Endocrinology, and WebMD.

Pituitary Tumors

Note: Dr. Melmed is a longtime professional member of the PNA.

Somatostatin and dopamine receptor regulation of pituitary somatotroph adenomas.
Ben-Shlomo A, Liu NA, Melmed S.
Pituitary. 2016 Nov 29. [Epub ahead of print] Review.

The identification of human pituitary adenoma-initiating cells.
Manoranjan B, Mahendram S, Almenawer SA, Venugopal C, McFarlane N, Hallett R, Vijayakumar T, Algird A, Murty NK, Sommer DD, Provias JP, Reddy K, Singh SK.
Acta Neuropathol Commun. 2016 Nov 28;4(1):125.

Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes.
Lambert K, Rees K, Seed PT, Dhanjal MK, Knight M, McCance DR, Williamson C.
Obstet Gynecol. 2016 Dec 2. [Epub ahead

Anterior and posterior suprasellar extensions of a symmetrical trilobed nonfunctional giant pituitary adenoma in the sagittal plane: a case report and review of literature.
Vakharia RM, Kremen R, Vakharia A, Adarkwah O, Anderson G.
Radiol Case Rep. 2016 Oct 22;11(4):419-424.

Postoperative outcome of body core temperature rhythm and sleep-wake cycle in third ventricle craniopharyngiomas.
Zoli M, Sambati L, Milanese L, Foschi M, Faustini-Fustini M, Marucci G, de Biase D, Tallini G, Cecere A, Mignani F, Sturiale C, Frank G, Pasquini E, Cortelli P, Mazzatenta D, Provini F.
Neurosurg Focus. 2016 Dec;41(6):E12.

Autocrine IL-6 mediates pituitary tumor senescence.
Sapochnik M, Haedo MR, Fuertes M, Ajler P, Carrizo G, Cervio A, Sevlever G, Stalla GK, Arzt E.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncota

Vanishing Pituitary Macroadenoma: A Case Report.
Sieg EP, Stepanyan H, Payne R, Ouyang T, Zacharia BE.
Cureus. 2016 Oct 20;8(10):e838.

Pituitary Surgery

Endoscopic endonasal pituitary adenomas surgery: the surgical experience of 178 consecutive patients and learning curve of two neurosurgeons.
Shou X, Shen M, Zhang Q, Zhang Y, He W, Ma Z, Zhao Y, Li S, Wang Y.
BMC Neurol. 2016 Nov 30;16(1):247.


SOCS2 polymorphisms are not associated with clinical and biochemical phenotypes in acromegalic patients.
Trarbach EB, Jorge AA, Duarte FH, Bronstein MD, Jallad RS.
Pituitary. 2016 Nov 29. [Epub ahead of print]

Silent somatotroph tumour revisited from a study of 80 patients with and without acromegaly and a review of the literature.
Chinezu L, Vasiljevic A, Trouillas J, Lapoirie M, Jouanneau E, Raverot G.
Eur J Endocrinol. 2017 Feb;176(2):195-201.

Cystatin-C and epicardial adipose tissue as noninvasive predictors of cardiovascular risk in acromegaly.
Aulinas A, Crespo I, Viladés D, Leta R, Urgell E, Biagetti B, Webb SM, Valassi E.
Clin Endocrinol (Oxf). 2016 Nov 7. doi: 10.1111/cen.13273. [Epub ahead of print]


Currently used and investigational drugs for Cushing´s disease.
Ciato D, Mumbach AG, Paez-Pereda M, Stalla GK.
Expert Opin Investig Drugs. 2016 Nov 29. [Epub ahead of print]


Prevalence and predictors of overweight and obesity in patients with pituitary dysfunctions.
Harbeck B, Danneberg S, Rahvar AH, Mönig H, Haas CS.
Endocr Metab Immune Disord Drug Targets. 2016 Nov 30. [E

Pituitary sex hormones enhance the pro metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase 1.
Abdelbaset-Ismail A, Pedziwiatr D, Schneider G, Niklinski J, Charkiewicz R, Moniuszko M, Kucia M, Ratajczak MZ.
Int J Oncol. 2016 Dec 2. doi: 10.3892/ijo.2016.3787. [Epub ahead of print]

Pituitary stalk interruption syndrome: From clinical findings to pathogenesis.
Wang CZ, Guo LL, Han BY, Su X, Guo QH, Mu YM.
J Neuroendocrinol. 2016 Dec 5. doi: 10.1111/jne.12451. [Epub ahead of print] Review.

Prolactin regulatory element-binding protein is involved in suppression of the adiponectin gene in vivo.
Zhang XZ, Imachi H, Lyu JY, Fukunaga K, Sato S, Ibata T, Kobayashi T, Yoshimoto T, Kikuchi F, Dong T, Murao K.
J Endocrinol Invest. 2016 Dec 2. [Epub ahead of print]


Available Now!

PPRG6-500 Cover
The Pituitary Patient Resource Guide Sixth Edition is now available! Be one of the first to have the most up-to-date information. The Pituitary Patient Resource Guide a one of a kind publication intended as an invaluable source of information not only for patients but also their families, physicians, and all health care providers. It contains information on symptoms, proper testing, how to get a diagnosis, and the treatment options that are available. It also includes Pituitary Network Association's patient resource listings for expert medical care.

Buy Now