R&D News

Saint John’s Health Center Appoints New Director of Neuroscience Institute
09.08.2009 Saint John’s Heath Center in Santa Monica, California, has expanded their team to include Amin Kassam, MD, as Director of their new Neuroscience Institute. He will be working alongside Dan Kelly, MD, director of Saint John’s Brain Tumor Center, who is a longtime member and great friend of the PNA.... Read More

FDA Investigates Heparin Link in Two Delaware Deaths
08.26.2009 May 12 - The FDA is investigating a possible link to heparin in the deaths of two Delaware residents who suffered cerebral hemorrhages following heparin treatment.... Read More

Transitioning the Growth-Hormone-Deficient Child into Adult Life
03.20.2009 Several studies have demonstrated that there is a highly variable transition period during which the GH-deficient teenager or young adult develops these adverse metabolic, functional, and behavioral characteristics.... Read More

Neurobehavioral Aspects of Pituitary Tumors in Childhood
03.20.2009 The main pituitary tumor effects of visual deficits and hormonal abnormalities combine to produce distinct constellations of neurocognitive and social/behavioral issues for consideration in subsequent medical and neurobehavioral/clinical psychological management.... Read More

Pituitary insufficiency after traumatic brain injury - Clinical Study
02.10.2009 Wachter D et al. - Neuropsychological complaints were present in 67% of the patients and were associated with intracerebral hemorrhagic lesions and not PI.... Read More

Abstract: Chronic hypopituitarism after traumatic brain injury: Risk assessment and relationship to outcome.
01.30.2009 Chronic pituitary dysfunction is increasingly recognized as a sequela of traumatic brain injury.... Read More

Craniopharyngioma surgery
01.30.2009 Honegger J et al. - Ideal surgical treatment of craniopharyngiomas remains a major challenge for neurosurgeons.... Read More

FDA Reports Nationwide Recall of Mislabeled ReliOn Insulin Syringes
12.13.2008 The U.S. Food and Drug Administration is notifying health care professionals and patients ...... Read More

NIH to Set Brain Tumor Research Priorities
12.13.2008 In Current Edition Of Viewpoint From Veritas Medicine... Read More

Cushing's disease one of hardest to diagnose
12.13.2008 Doctors rarely see condition and end up treating secondary disease instead of cause... Read More

Cushing's Disease One of the Hardest to Diagnose
12.13.2008 Doctors rarely see condition and end up treating secondary disease instead of cause... Read More

European Journal of Neuro-Endocrinology, Jan 2006 - THE COST OF MEDICAL CARE FOR THE ACROMEGALIC PATIENT
12.13.2008 by Robert Knutzen, CEO PNA and Shereen Ezzat, M.D.... Read More

TESTOSTERONE THERAPY FOR ANDROGEN DEFICIENT MEN - New Clinical Guideline from the Endocrine Society
12.13.2008 by Cathy Kristiansen, Editor... Read More

TOUCH BRIEFINGS: US ENDOCRINE DISEASE
12.13.2008 Recent articles published by Touch Briefings:... Read More

U.S. Food and Drug Administration Enforcement Report
12.13.2008 Recalls and Field Corrections: Drugs -- Class III ... Read More

King Pharmaceuticals, announcement of discontinuance of the manufacture of FLORINEF Acetate (Fludrocortisone Acetate Tablets, USP)
12.13.2008 Decision based upon many factors, including understanding of current medical therapy and general availability of generic alternatives.... Read More

FDA Reports Nationwide Recall of Mislabeled ReliOn Insulin Syringes
12.13.2008 The U.S. Food and Drug Administration is notifying health care professionals and patients that Tyco Healthcare Group LP (Covidien) is recalling one lot of ReliOn syringes... Read More

Important: Keep the FDA Informed!
12.13.2008 If you are having trouble with ANY of your medications:... Read More

Testosterone Therapy For Androgen Deficient Men
11.25.2008 Clinical Guideline from the Endocrine Society... Read More

MicroRNAs and Possible Role in Pituitary Adenoma
12.10.2008 Zatelli MC et al. - This review reports the current knowledge of microRNA (miRNA) expression in pituitary adenomas... Read More

Behavioral neuroendocrinology and treatment of anorexia nervosa
12.10.2008 Sodersten P et al. - Outcome in anorexia nervosa remains poor and a new way of looking at this condition is therefore needed... Read More

Hypothyroidism in Male Patients
12.13.2008 A Descriptive, Observational and Cross-Sectional Study in a Series of 260 Men... Read More

Effect of treatment with depot somatostatin analogue octreotide on (PHP) in (MEN1) patients
12.13.2008 Faggiano A et al. - Six months of OCT-LAR therapy controlled hypercalcaemia and hypercalciuria in two-thirds of patients with MEN1-related PHP... Read More

Effect of Statins on PSA May Confound Biopsy Decision
12.10.2008 DURHAM, N.C. -- Statin therapy lowers prostate-specific antigen levels... Read More

Childbirth and HRT May Boost Need for Joint Replacement
01.30.2009 OXFORD, England -- Increasing parity for women who later take postmenopausal hormone replacement therapy appears to have a higher incremental risk of severe hip and knee osteoarthritis... Read More

Many Women with Sexual Dysfunction Simply Don’t Care
01.29.2009 BOSTON -- Although about 45% of women have some form of sexual problem... Read More

Acromegaly secondary to an incidentally discovered tumour
12.13.2008 Growth-hormone-releasing hormone secreting bronchial carcinoid tumour associated to a pituitary incidentaloma... Read More

CDC Finds Soaring Diabetes Rates
03.20.2009 CDC Finds Soaring Diabetes Rates ... Read More

Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): A randomized controlled trial
12.13.2008 Cheung AM et al. - Daily 5 mg dose of vitamin K1 supplementation for 2 to 4 y does not protect against age-related decline in BMD... Read More

Diagnosis of secondary adrenal insufficiency in patients with hypothalamic-pituitary disease
12.07.2008 Comparison between serum and salivary cortisol during the high-dose short synacthen test... Read More

Clinical Use of Cabergoline as Primary and Adjunctive Treatment for Acromegaly
12.13.2008 Moyes V et al. - Cabergoline can be an effective and well tolerated primary or adjunctive therapy for acromegaly... Read More

Patients' Perception of Hospital Care in the United States
12.12.2008 Jha AK et al. - This portrait of patients' experiences in U.S. hospitals offers insights into areas that need improvement... Read More

Male Sex Hormones May Influence the Symptoms of Irritable Bowel Syndrome in Young Men
12.07.2008 Kim BJ et al. - Sex hormone status in young men differ from those in older men and may play an important role in the pathophysiology of IBS... Read More

Neoadjuvant and adjuvant hormone therapy: how and when
12.07.2008 Poppel HV - In a review to discuss whether hormone therapy (HT) in either a neoadjuvant or adjuvant setting can offer a survival benefit for pts with prostate cancer (PCa)... Read More

Lipid lowering in diabetes mellitus
12.07.2008 Betteridge DJ et al. – This review article reports that benefits of statin therapy in diabetes are confirmed and extended ... Read More

Cardiovascular Outcomes in Trials of Oral Diabetes Medications
12.07.2008 Selvin E et al. - Meta-analysis suggested that, compared with other oral diabetes agents and placebo, metformin was moderately protective and rosiglitazone possibly harmful... Read More

Management of Graves hyperthyroidism in pregnancy
01.29.2009 Focus on both maternal and foetal thyroid function, and caution against surgical thyroidectomy in pregnancy.... Read More

Erectile dysfunction as a coronary artery disease risk equivalent
02.03.2009 Lee JH et al. – Erectile dysfunction is significantly associated with abnormal coronary artery calcification... Read More

Undescended testes: A consensus on management
12.12.2008 Ritzen M et al. - The unanimous conclusion of the group was that surgery is generally the preferred mode of treatment, rather than hCG or GnRH.... Read More

Safety of statins
12.07.2008 Brown WV et al. – A review summarizes evidence for reported adverse effects during statin use in hypercholesterolemia... Read More

GnRH analogues: Applications in assisted reproductive techniques
02.10.2009 This shift in practice is occurring alongside gathering momentum in favour of milder stimulation protocols and a new perception of what constitutes successful treatment.... Read More

Hormone replacement therapy post Women's Health Initiative study: where do we stand
01.29.2009 Calleja-Agius J et al. - There is a definite decline in the use of hormone replacement therapy among menopausal women.... Read More

Depression and Bone Metabolism
12.07.2008 Williams LJ et al. - The possible association between psychiatric illness, in particular depression, and osteoporosis has been the subject of a growing body of research... Read More

Lithium Treatment and Risk of Dementia
12.07.2008 Kessing LV et al. - Continued lithium treatment was associated with reduction of the rate of dementia... Read More

Pituitary-adrenal function in patients with acute subarachnoid hemorrhage
12.13.2008 Bendel S et al. - Calculation of serum free cortisol concentration was not helpful in identifying patients with potential hypocortisolism.... Read More

The appearance of the adrenal glands on CT in multiple endocrine neoplasia type 1
12.13.2008 In patients with MEN1, adrenal limb hyperplasia and adrenal nodules are significantly more common than in the normal population... Read More

Retesting the childhood-onset GH deficient patient
01.30.2009 GH deficiency (GHD) in adults has to be shown by a single provocative test, provided that it is validated.... Read More

A single test procedure to diagnose gestational diabetes mellitus
01.31.2009 Universal screening for gestational diabetes mellitus (GDM), detects more cases and improves maternal and offspring prognosis.... Read More

Diagnosis of Growth Hormone Deficiency in Adults
12.13.2008 Provocative Testing with GHRP6... Read More

Clinical impact of two different intraoperative parathyroid hormone assays
12.13.2008 Intraoperative parathyroid hormone (PTH) monitoring predicts successful surgery for primary hyperparathyroidism (pHPT). ... Read More

FDA Review Finds Minimal Heart Risk with Osteoporosis Drugs
01.29.2009 ROCKVILLE, Md. -- The FDA’s promised analysis of atrial fibrillation events associated with bisphosphonate drugs for osteoporosis has found that the risk is minimal.... Read More

FDA Report Questions Osteoporosis Drug
01.29.2009 FDA Report Questions Osteoporosis Drug... Read More

Review Indicates Number of Endocrinology Disease Studies Increasing
12.10.2008 Review Indicates Number of Endocrinology Disease Studies Increasing... Read More

Research Suggests Hormone Therapy May Lead to More Deadly Prostate Cancer
12.10.2008 Research Suggests Hormone Therapy May Lead to More Deadly Prostate Cancer... Read More

Robert Costello – The Prophet of Pituitary Adenomas
12.13.2008 Robert Costello conducted a careful and systematic analysis of pituitary glands obtained at post mortem examination from patients who had no obvious symptoms of endocrine disorders.... Read More

Abstract: Medical therapy of pituitary adenomas: Effects on tumor shrinkage
01.29.2009 The efficacy of dopamine-agonists (DA) in patients with prolactinomas and that of somatostatin analogues (SSA) in those with GH- and TSH-secreting adenomas is well established... Read More

Practical Pituitary Pathology
11.01.2008 Practical Pituitary Pathology... Read More

MDLinx: ENDOCRINOLOGY - LIPIDS 10/08
12.13.2008 MDLinx: ENDOCRINOLOGY - LIPIDS 10/08... Read More

MDLinx: NEURORADIOLOGY 10/08
12.13.2008 MDLinx: NEURORADIOLOGY 10/08... Read More

MDLinx: NEUROENDOCRINOLOGY 10/08
12.12.2008 MDLinx: NEUROENDOCRINOLOGY 10/08... Read More

Psychosis and the Pituitary
11.25.2008 Psychosis and the Pituitary... Read More

One in Five - Pituitary Hormonal Health Statistics
12.13.2008 One in Five - Pituitary Hormonal Health Statistics... Read More

Pituitary Growth Hormone Advance
11.24.2008 Sensus Corporation’s Growth Hormone Antagonists ... Read More

Patient Survey - Possible link in avascular necrosis surgery and unrecongnized Cushing's Disease or Syndrome.
03.13.2009 It may be that patients who undergo hip surgery for avascular necrosis may have unrecognized Cushing's Disease or Cushing's Syndrome.... Read More

ACR: Biologic Therapy May Be Better for Bones than Bisphosphonate
02.05.2009 SAN FRANCISCO -- Women with a low bone mass may get a better treatment response with denosumab... Read More

Obesity and Hypogonadism
01.30.2009 Obesity and Hypogonadism... Read More

The Stress Response and its Implications for Pituitary Tumors
03.05.2010 ...Tumors of the pituitary may mimic the stress response, causing many of the same symptoms seen in people suffering from chronic stress syndromes.... Read More

DuoCort Survey
08.20.2009 The National Adrenal Diseases Foundation (NADF) has been asked to invite adrenal insufficient patients to fill out a survey being conducted by DuoCort AB of Sweden.... Read More

Hypothalamic Obesity
03.20.2009 Obesity has rapidly become the largest (both figuratively and literally) public health problem, both in the U.S. and in numerous Westernized countries. The causes of this epidemic are myriad...... Read More

Pituitary apoplexy: correlation between magnetic resonance imaging and histopathological results.
01.30.2009 The aim of this study was to correlate the magnetic resonance (MR) imaging findings in pituitary apoplexy with histopathological results and determine whether the histopathology influences clinical presentation and outcome.... Read More

Robert Costello – The Prophet of Pituitary Adenomas
01.30.2009 A report by Edward R. Laws, Department of Neurosurgery, Brigham and Women’s Hospital and Robert Knutzen, Chair/CEO, Pituitary Network Association... Read More

Pituitary Function and Tumors
12.13.2008 Control of Anterior Pituitary Hormone Secretion... Read More

Beyond the Cancer Model
12.05.2008 Toxins: Preoccupation with carcinogens blinds us to other threats.... Read More

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