× Adult GH deficiency is now a well-recognized clinical syndrome that includes symptoms of increased body fat, decreased muscle and bone mass with reduced strength and endurance, impaired psychological well-being, reduced vitality, and poor quality of

fatty liver

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Replied by PNA-Tammy on topic fatty liver

Hi Mike,
Here is another reply from another one of our advisors.

GH deficiency is established on both clinical and biochemical criteria, but despite significant advances in our understanding of adult GH deficiency, accurate diagnosis remains challenging. Selecting the appropriate patient, performing a reliable diagnostic test, and understanding the clinical caveats as well as the analytical limitations are the crucial steps.
The value of serum IGF-1 in the diagnosis of GH deficiency is a matter of contention among endocrinologists. Having normal levels of IGF-I does not completely exclude a diagnosis of GH deficiency in adults, however, IGF-I can be of some diagnostic assistance if levels are below the age-adjusted normal range.
A dynamic GH stimulation test GH-RH+ARG or glucagon in US (where GHRH is unavailable) is the best confirmatory test.

I think Kelly makes a good point to. It is best to work with an Endo that uses your symptoms in addition to test results to determine the best treatment.

Take care, Tammy
5 years 10 months ago #10030

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Replied by kjknight on topic fatty liver

Hello Mike,

I believe the tolerance test you are talking about is glucagon and takes blood levels over several hours. It somehow measures how the Pituitary responds to the glucose, but I think it's the stored glucose in fat cells that has something to do with GH. Obviously, I'm not a doctor, but I do have GH deficiency after removal of a posterior ACTH silent tumor. It took about a year after surgery to finally show enough symptoms for the test. My doc says the IGF-1 is just a marker, and mine was always normal too. I'm lucky to have an Endo that pays more attention to symptoms than test results. The Glucagon test showed that I was very low and I take GH daily for about 6 months now. I haven't seen a great decrease in the fat stores, but it has been extremely helpful in my energy level and overall mental health and concentration. I find when I don't take it, my thoughts are scattered and I just feel more depressed and tired. I suggest seeing a neuro-endo specialist.. I started out seeing a regular endo locally - live in Maine - and ended up going to Boston. Brigham and Women's has an excellent neuro-endo program. Good luck, I hope you are able to get the test you need.
Kelly
5 years 10 months ago #10029

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Replied by 1eyedmike on topic fatty liver

Thanks Tammy, I've had the IGF-1 test a couple of times and it comes back a bit low so I've done the good place to start what I'm wondering is it the Gold Standard for measuring HGH in adults my Endo thinks so but I've read otherwise and want to reinforce my reading. Thanks Michael
5 years 10 months ago #10028

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Replied by PNA-Tammy on topic fatty liver

Hi Michael,
I posed your question to one of our Advisors and he said that the IGF-1 is a good place to start. I think the next step, if there needs to be one, will be determined by the outcome of the IGF-1 test results. I hope this helps.
Take care,
Tammy
5 years 11 months ago #10027

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Replied by 1eyedmike on topic fatty liver

Thanks Tammy I look forward to hearing from you. Michael
5 years 11 months ago #10026

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Replied by PNA-Tammy on topic fatty liver

Hi Mike,
Sorry about the delay, this question is beyond my knowledge, so I am trying to find someone who can answer it for you. I will let you know as soon as I am able to find anything out.
Tammy
5 years 11 months ago #10025

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