× As their name indicates, these relatively common pituitary adenomas do not result in excess hormone production. Instead they typically cause symptoms because of increasing size and pressure effect on the normal pituitary gland and on structures near

Cabergoline use in Non functioning tumors

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Replied by kfbrady on topic Cabergoline use in Non functioning tumors

"Neurosurgeon told me that the tumor had to be operated via transsphenoidal surgery and He explained me the risks, adverse effects, etc. When I decided to undergo surgery, doctor consider that it was not convenient to do it because of my young age and it could be difficult for my health..."

First off, the usual disclaimers. I'm not a medical professional, just a former patient so take any advice I can give accordingly, but why did your doctor consider the surgery inconvenient? I guess I just don't understand that - maybe something is lost in translation between Spanish and English? Your tumor is right at the size of a macro adenoma; mine was just a little larger and my highly experienced neurosurgeon wanted it removed as soon as possible before it started to affect other parts of my brain.

Of course I don't know your complete details but why is 25 considered to be too young for the surgery? There are stories on this website of teenagers undergoing successful adenomectomies. While there are always risks the surgery in my case - I was 61 when I had it - was quite straightforward and after 2 days in hospital my transsphenoidal procedure was considered to be highly successful. That was over 5 years ago and I've had no issues since.

In your case I would definitely be looking for another opinion as I think your treating this with a drug usually prescribed for prolactinomas may have significant risks to your health and unwanted side effects.

Anyway, good luck with your treatment whatever you decide.
1 year 2 weeks ago #10394

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Replied by PNA-Tammy on topic Cabergoline use in Non functioning tumors

Hello,

I did receive another response from one of our advisers about a specialist in Columbia that may be able to help you. Here is the information they provided:

Dr. PEDRO NEL RUEDA is an endocrinologist in Bogota, Colombia who can advise the patient on her pituitary and thyroid problems.
Small studies suggested cabergoline may reduce the size of nonfunctioning pituitary adenomas, but the data is limited.
Follow up with endocrinology, ophthalmology and neurosurgery is necessary in all cases of pituitary adenoma, especially those with evidence of hemorrhage of apoplexy of the tumor.

I hope this also helps.

Take care,
Tammy Mazzella
Pituitary Network Association
(805) 499-9973
[email protected]
1 year 1 month ago #10391

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Replied by pnaadmin on topic Cabergoline use in Non functioning tumors

Hello and thank you for using our Forum. I am not a medical professional so I cannot personally answer your questions. I did ask some of our advisers though and this is the response I received from one of them.

From the information provided
- The thyroid issues are caused by primary thyroid problem ( Hashimotos thyroiditis) and doesn’t seems to be caused by the pituitary lesion
- Regarding the pituitary lesion: Cabergoline is usually not helpful in shrinking a tumor unless it is a prolactinoma ( prolactin producing tumor).
- If is a nonfunctioning tumor and not increasing in size, it is reasonable to monitor with repeat MRI and make sure the other pituitary hormones remain normal.

I hope this information is helpful. Feel free to contact us if you have further questions or if you would like more information.

Take care,
Tammy Mazzella
Pituitary Network Association
(805) 499-9973
[email protected]
1 year 1 month ago #10388

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  • Limartinezr18
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Cabergoline use in Non functioning tumors was created by Limartinezr18

Hello everybody! Greetings from Bogotá, Colombia!

First, sorry for my lack english I´m still learning and I am sure you can help me out with my issue.
I´m a 25 years old female and in 2014 I was diagnosed with a 10mm pituitary adenoma. The symptom by which doctors diagnosed me was a repentine amaurosis in my right eye (suddenly things were black and literally I became blind for about 3 minutes only in my right eye). I was so scared, of course, but the last amaurosis episode was on May 2015, thanks to God.
I've been tested more than 6 times for visual field tests and all of them show good results, it seems I do not have visual field loss. But the gadolinium NMR show that the tumor has bleed and probably due to this the amaurosis was presented. Neurosurgeon told me that the tumor had to be operated via transsphenoidal surgery and He explained me the risks, adverse effects, etc. When I decided to undergo surgery, doctor consider that it was not convenient to do it because of my young age and it could be difficult for my health.
Furthermore, the tumor has not grown over this last years, since my first NMR (2013) the mass remains with 10mm diameter. He prescribed me, instead, cabergoline 1mg/week for 6 months even when my prolactine level is 15,56 ng/mL, and never has been abnormally. My complete hormonal profile had been normal until this year (may) when the TSH level was upper the limit, 7,77 uUI/mL and the TPO antibodies was 150UI/mL. I have some symptoms like dry skin, hair loss, and amenorrhea (my menstrual cycle always has been irregular).
I would like to know ¿what do you think about my situation? ¿Could cabergoline help me with the reduction of the tumor size? ¿It would be probably that cabergoline "activate" the adenoma and cause to me a major hormonal disorder?... I'm looking fordward for your answer from your experience. I really apreciate your time, thanks in advance.
1 year 1 month ago #10387

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