This month the PNA Spotlight focuses on Dr. Lewis Z. Leng, a board-certified neurosurgeon at Sutter Health/California Pacific Medical Center. He also serves as Department Head of Neurosurgery for Sutter West Bay Medical Group and as a Clinical Assistant Professor of Neurology at Geisel School of Medicine at Dartmouth. In addition he is Co-Director of Endoscopic Skull Base and Pituitary Surgery, and Chair of the Neurosciences Quality Improvement Committee at CPMC.
Dr. Leng received his B.A. from University of California at Berkeley. He earned his medical degree from Perelman School of Medicine at the University of Pennsylvania during which time he was a 21st Century Scholar and received a Howard Hughes Medical Institute Fellowship. Dr. Leng completed his residency in neurosurgery at New York Presbyterian Hospital-Weill Cornell Medical Center and Memorial Sloan-Kettering Cancer Center. He was kind enough to answer a series of questions from the PNA. His answers follow.
This month the PNA Medical Corner spotlights an article co-authored by Dr. Martin Weiss, chairman of neurosurgery at USC and a member of the PNA. The study used neural network modeling to look at the factors that lead to negative outcomes, which include the presence of a tumor that has recurred after surgery and visual deficits that did not improve after surgery. The authors analyzed the outcomes for 341 patients with acromegaly, Cushings or a mammosomatotroph adenoma, 81 of whom had sub-optimal outcomes. Their modeling was able to predict with 87.1% accuracy which patients are more at risk for a poor outcome.
Neural network modeling for prediction of recurrence, progression, and hormonal non-remission in patients following resection of functional pituitary adenomas
Shane Shahrestani 1 2, Tyler Cardinal 3, Alexander Micko 3 4, Ben A Strickland 3, Dhiraj J Pangal 3, Guillaume Kugener 3, Martin H Weiss 3, John Carmichael 3, Gabriel Zada 3 Affiliations expand • PMID: 33528731 DOI: 10.1007/s11102-021-01128-5
An article in Cushing’s Disease News looks a case study from Japan of a woman who had Cushings and COVID-19 simultaneously. Read more:
Obesity Raises Risk for Pituitary Disease
An article in Healio looks at a study that concluded that adults who suffer from obesity, especially as young adults, have a higher risk for developing a pituitary tumor Read more:
Almost 1/5th of Pediatric Brain Tumors Occur in the Pituitary
An article in Healio looks at a study that found that brain tumors in children strike in the pituitary almost 20% of the time, and that they are significantly more prevalent in girls, with diagnosis most likely to occur in the early teens. Read more:
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Disclaimer: PNA does not engage in the practice of medicine. It is not a medical authority, nor does it claim to have medical expertise. In all cases, PNA recommends that you consult your own physician regarding any course of treatment or medication.
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