Functional Outcomes After Surgery for Pituitary Tumors

21 April 2014

The anatomy of the pituitary gland from a patient's and surgeon's perspective
The mechanisms that allow this anatomy to cause three of the common types of symptoms that patients with lesions in the pituitary gland like nonfunctional pituitary adenomas or Rathke's cleft cysts can present with: headaches, endocrine dysfunction, and visual impairment
The impact of transsphenoidal surgery on each of these three types of symptoms that patients with nonfunctional adenomas present with, and factors predictive of postoperative improvement.

Presenter Bio

Dr. Manish Aghi is a neurosurgeon specializing in the treatment of pituitary adenomas and other tumors of the anterior skull base by minimally invasive endonasal approaches. He has an MD and PhD from Harvard Medical School in Boston and did his neurosurgery residency at the Harvard affiliated Massachusetts General Hospital (MGH). Since joining UCSF six years ago, he has performed nearly 500 endonasal operations for pituitary tumors and, as the leader of an active clinical research program, he has published 24 articles on surgical technique and outcomes for pituitary tumor patients. He is currently directing a national effort sponsored by the Congress of Neurological Surgeons to establish evidence-based guidelines for neurosurgeons caring for patients with pituitary tumors.

Dr. Aghi also runs an NIH funded basic science laboratory investigating the molecules that allow pituitary tumors to grow and invade, and he is working with industry collaborators to develop molecular inhibitors that may someday be of benefit to prevent these processes. He is principal investigator of a pair of phase I/II clinical trials of experimental treatments for malignant brain tumors.

 

  • Manish Aghi, MD, PhD

    Neurosurgeon
    Director, Center for Minimally Invasive Skull Base Surgery (MISB), California Center for Pituitary Disorders (CCPD)
    Associate Professor, University of California, San Francisco Department of Neurological Surgery

     

Description

The anatomy of the pituitary gland from a patient's and surgeon's perspective
The mechanisms that allow this anatomy to cause three of the common types of symptoms that patients with lesions in the pituitary gland like nonfunctional pituitary adenomas or Rathke's cleft cysts can present with: headaches, endocrine dysfunction, and visual impairment
The impact of transsphenoidal surgery on each of these three types of symptoms that patients with nonfunctional adenomas present with, and factors predictive of postoperative improvement.

Presenter Bio

Dr. Manish Aghi is a neurosurgeon specializing in the treatment of pituitary adenomas and other tumors of the anterior skull base by minimally invasive endonasal approaches. He has an MD and PhD from Harvard Medical School in Boston and did his neurosurgery residency at the Harvard affiliated Massachusetts General Hospital (MGH). Since joining UCSF six years ago, he has performed nearly 500 endonasal operations for pituitary tumors and, as the leader of an active clinical research program, he has published 24 articles on surgical technique and outcomes for pituitary tumor patients. He is currently directing a national effort sponsored by the Congress of Neurological Surgeons to establish evidence-based guidelines for neurosurgeons caring for patients with pituitary tumors.

Dr. Aghi also runs an NIH funded basic science laboratory investigating the molecules that allow pituitary tumors to grow and invade, and he is working with industry collaborators to develop molecular inhibitors that may someday be of benefit to prevent these processes. He is principal investigator of a pair of phase I/II clinical trials of experimental treatments for malignant brain tumors.

 

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