May 2019 Pituitary Research Articles

Knowledge is power and we believe keeping abreast of news on the research front is imperative. Each month in Highlights we feature a few of the top news stories, which you can read below. In addition, we update our website on a regular basis with the latest breaking news related to pituitary and hormonal disorders by gathering stories we think you'll be interested in from MD Linx, Medscape, MedPage Today, PubMed, Touch Endocrinology, and WebMD.


Pituitary Surgery


Significance and indications of surgery for asymptomatic nonfunctioning pituitary adenomas.
Ogiwara T, Nagm A, Nakamura T, Mbadugha T, Horiuchi T, Hongo K.
World Neurosurg. 2019 May 8. pii: S1878-8750(19)31257-4. doi: 10.1016/j.wneu.2019.04.250. [Epub ahead of print]

Complications Associated With Transsphenoidal Pituitary Surgery: Review of the Literature.
Agam MS, Zada G.
Neurosurgery. 2018 Sep 1;65(CN_suppl_1):69-73. doi: 10.1093/neuros/nyy160. No abstract available.

Evaluation of different hydrocortisone treatment strategies in transsphenoidal pituitary surgery.
Fridman-Bengtsson O, Höybye C, Porthén L, Stjärne P, Hulting AL, Sunnergren O.
Acta Neurochir (Wien). 2019 May 7. doi: 10.1007/s00701-019-03885-6. [Epub ahead of print]

Impacts of Surgery on Symptom Burden and Quality of Life in Pituitary Tumor Patients in the Subacute Post-operative Period.
Waddle MR, Oudenhoven MD, Farin CV, Deal AM, Hoffman R, Yang H, Peterson J, Armstrong TS, Ewend MG, Wu J.
Front Oncol. 2019 Apr 23;9:299. doi: 10.3389/fonc.2019.00299. eCollection 2019.

Utilization of the Nasoseptal Flap for Repair of Cerebrospinal Fluid Leak after Endoscopic Endonasal Approach for Resection of Pituitary Tumors.
Kessler RA, Garzon-Muvdi T, Kim E, Ramanathan M, Lim M.
Brain Tumor Res Treat. 2019 Apr;7(1):10-15. doi: 10.14791/btrt.2019.7.e19.

Pituitary Tumors

RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteins.
D'Angelo D, Mussnich P, Sepe R, Raia M, Del Vecchio L, Cappabianca P, Pellecchia S, Petrosino S, Saggio S, Solari D, Fraggetta F, Fusco A.
J Mol Med (Berl). 2019 May 10. doi: 10.1007/s00109-019-01789-7. [Epub ahead of print]

Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G.
Rev Med Inst Mex Seguro Soc. 2019 Apr 1;57(1):48-55. English, Spanish.


Cushing's Syndrome: A Large Adenoma of Adrenal Gland.
Soedarso MA, Nugroho KH, Prabowo E, Listiana DE, Soesilowati D, Santoso AG.
Acta Med Indones. 2019 Jan;51(1):75-76.

CRH stimulation improves 18F-FDG-PET detection of pituitary adenomas in Cushing's disease.
Boyle J, Patronas NJ, Smirniotopoulos J, Herscovitch P, Dieckman W, Millo C, Maric D, Chatain GP, Hayes CP, Benzo S, Scott G, Edwards N, Ray Chaudhury A, Lodish MB, Sharma S, Nieman LK, Stratakis CA, Lonser RR, Chittiboina P.
Endocrine. 2019 May 6. doi: 10.1007/s12020-019-01944-7. [Epub ahead of print]


Could calgranulins and advanced glycated end products potentiate acromegaly pathophysiology?
Kruse CPS, Cottrill DA, Kopchick JJ.
Growth Horm IGF Res. 2019 Apr 20;46-47:1-4. doi: 10.1016/j.ghir.2019.04.002. [Epub ahead of print]

Hormonal Health

Actions and potential therapeutic applications of growth hormone-releasing hormone agonists.
Schally AV, Zhang X, Cai R, Hare JM, Granata R, Bartoli M.
Endocrinology. 2019 May 9. pii: en.2019-00111. doi: 10.1210/en.2019-00111. [Epub ahead of print]

Treatment of gonadotropin deficiency during the first year of life: long-term observation and outcome in five boys.
Kohva E, Huopio H, Hietamäki J, Hero M, Miettinen PJ, Raivio T.
Hum Reprod. 2019 May 1;34(5):863-871. doi: 10.1093/humrep/dez040.

Limited Utility of Biochemical Screening for Pituitary Deficiencies and Adverse Effects in Idiopathic GH Deficiency.
Zborovski S, Palmert MR, Harrington J.
J Endocr Soc. 2019 Mar 28;3(5):1022-1030. doi: 10.1210/js.2018-00390. eCollection 2019 May 1.

Rathke’s Cleft Cyst

Spontaneously Regressed Rathke's Cleft Cyst.
Lee C, Park SH.
J Korean Neurosurg Soc. 2019 May 8. doi: 10.3340/jkns.2018.0225. [Epub ahead of print]


Available Now!

PPRG6-500 Cover
The Pituitary Patient Resource Guide Sixth Edition is now available! Be one of the first to have the most up-to-date information. The Pituitary Patient Resource Guide a one of a kind publication intended as an invaluable source of information not only for patients but also their families, physicians, and all health care providers. It contains information on symptoms, proper testing, how to get a diagnosis, and the treatment options that are available. It also includes Pituitary Network Association's patient resource listings for expert medical care.

Buy Now

  • November

  • December


Continuing Education Program

Knowledge Icon 500

If you are a nurse or medical professional, register for PNA CEU Membership and  earn CEU credits to learn about the symptoms, diagnosis and treatment options for patients with pituitary disorders. Help PNA reduce the time it takes for patients to get an accurate diagnosis.

button registerNow

For more information click here!