November 2014 Pituitary Research Articles

Knowledge is power and we believe keeping abreast of news on the research front is imperative. Each month in Highlights we feature a few of the top news stories, which you can read below. In addition, we update our website on a regular basis with the latest breaking news related to pituitary and hormonal disorders by gathering stories we think you'll be interested in from MD Linx, Medscape, MedPage Today, PubMed, Touch Endocrinology, and WebMD.



Using Growth Hormone Levels to Detect Macroadenoma in Patients with Acromegaly.
Park JY, Kim JH, Kim SW, Chung JH, Min YK, Lee MS, Lee MK, Kim KW.
Endocrinol Metab (Seoul). 2014 May 27. [Epub ahead of print]


Long-term follow-up on Cushing disease patient after transsphenoidal surgery.
Jeong I, Oh M, Kim JH, Cho JH, Choi JH, Yoo HW.
Ann Pediatr Endocrinol Metab. 2014 Sep;19(3):164-8. doi: 10.6065/apem.2014.19.3.164. Epub 2014 Sep 30.

Persistent centripetal fat distribution and metabolic abnormalities in patients in long-term remission of Cushing's syndrome
Clinical Endocrinology 10/20/2014

Pituitary Tumors- General

Evaluation of the Antiangiogenic Effects of Octreotide on Growth Hormone-producing Pituitary Adenoma using Arterial Spin-labeling Perfusion Imaging.
Sakai N, Yamashita S, Takehara Y, Sakahara H, Baba S, Oki Y, Takahashi G, Koizumi S, Sameshima T, Namba H.
Magn Reson Med Sci. 2014 Oct 27. [Epub ahead of print]

Predictive value of diffusion-weighted MRI for tumor consistency and resection rate of nonfunctional pituitary macroadenomas.
Alimohamadi M, Sanjari R, Mortazavi A, Shirani M, Moradi Tabriz H, Hadizadeh Kharazi H, Amirjamshidi A.
Acta Neurochir (Wien). 2014 Oct 23. [Epub ahead of print]
68Ga-DOTATATE PET/CT, 99mTc-HYNIC-Octreotide SPECT/CT, and whole-body MR imaging in detection of neuroendocrine tumors: A prospective trial Extended Summary
The Journal of Nuclear Medicine 10/22/2014


The role of the Sonic Hedgehog signalling pathway in patients with midline defects and congenital hypopituitarism
Clinical Endocrinology 10/20/2014

Heterozygous defects in PAX6 gene and congenital hypopituitarism.
Takagi M, Nagasaki K, Fujiwara I, Ishii T, Amano N, Asakura Y, Muroya K, Hasegawa Y, Adachi M, Hasegawa T.
Eur J Endocrinol. 2014 Oct 23. pii: EJE-14-0255. [Epub ahead of print]

Clinical outcome and evidence of high rate post-surgical anterior hypopituitarism in a cohort of TSH-secreting adenoma patients: Might somatostatin analogs have a role as first-line therapy?
Gatto F, Grasso LF, Nazzari E, Cuny T, Anania P, Di Somma C, Colao A, Zona G, Weryha G, Pivonello R, Ferone D.
Pituitary. 2014 Oct 19. [Epub ahead of print]

Hormonal Health

Analysis of short- and long-term metabolic effects of growth hormone replacement therapy in adult patients with craniopharyngioma and non-functioning pituitary adenoma.
Profka E, Giavoli C, Bergamaschi S, Ferrante E, Malchiodi E, Sala E, Verrua E, Rodari G, Filopanti M, Beck-Peccoz P, Spada A.
J Endocrinol Invest. 2014 Oct 21. [Epub ahead of print]

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models
Neuropharmacology 10/14/2014

Efficacy and safety of growth hormone treatment in children with hypochondroplasia: comparison with an historical cohort
Hormone Research in Paediatrics 10/15/2014

EMA Panel Says No Heart Risk With Testosterone
But this is not the final word from the European Medicines Agency. 

Testosterone Tx Acts as Prostate Tumor Promoter in Rats
Study findings may have significant public health implications for the use of testosterone therapy in men. 

Growth hormone, insulin-like growth factor-1 and the aging brain 
Experimental Gerontology 10/29/2014


Preserving fertility in the hypogonadal patient: an update.
Ramasamy R, Armstrong JM, Lipshultz LI.
Asian J Androl. 2014 Oct 3. doi: 10.4103/1008-682X.142772. [Epub ahead of print]


Two Diabetes Bills Before Congress
Endocrinologists step up legislative efforts.

Thyroid Issues

Neonatal screening and a new cause of congenital central hypothyroidism.
Tajima T, Nakamura A, Morikawa S, Ishizu K.
Ann Pediatr Endocrinol Metab. 2014 Sep;19(3):117-21. doi: 10.6065/apem.2014.19.3.117. Epub 2014 Sep 30. Review.

The effect of L-thyroxine treatment on left ventricular functions in children with subclinical hypothyroidism
Archives of Diseases in Childhood 10/22/2014


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