• Home
  • Research
  • Research News
  • Prolactin serum levels in first-episode neuroleptic-naive patients with pituitary microadenoma and comorbid psychosis.

Prolactin serum levels in first-episode neuroleptic-naive patients with pituitary microadenoma and comorbid psychosis.

Cheng M, Wen S, Tang X, Zhong Z, Gan Z.

Source

Department of Psychiatry, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou 510630, Guangdong Province, People's Republic of China.


Abstract

This study was designed to explore the relationship between pituitary microadenoma and psychosis and to evaluate the role that prolactin plays in pituitary microadenoma and comorbid psychosis. In this study, the prolactin serum levels were compared between 74 first-episode drug-naive patients with a pituitary microadenoma with psychosis (PMP), and 58 patients with a pituitary microadenoma with no psychosis (PMNP). Patients with PMP had significantly higher prolactin serum levels; male patients with PMP had a mean [S.D.] prolactin level of 705.4uIU/ml [226.1] vs. 433.1uIU/ml [58.4] for male patients with PMNP, while female patients with PMP had a mean prolactin level of 1890.1uIU/ml [1138.7] vs. 978.6uIU/ml [657.9] for female patients with PMNP. The size of microadenoma in the patients with PMP was larger than those in the patients with PMNP, regardless of sex. Our data suggested that a higher prolactin serum level is a characteristic of first-episode neuroleptic-naive patients with PMP.

Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Print

Available Now!

PPRG6-500 Cover
The Pituitary Patient Resource Guide Sixth Edition is now available! Be one of the first to have the most up-to-date information. The Pituitary Patient Resource Guide a one of a kind publication intended as an invaluable source of information not only for patients but also their families, physicians, and all health care providers. It contains information on symptoms, proper testing, how to get a diagnosis, and the treatment options that are available. It also includes Pituitary Network Association's patient resource listings for expert medical care.

Buy Now