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April 2021


Young Woman Fights Craniopharyngioma and Turner Syndrome

An article in the Daily Record highlights the case of a 19-year-old Scottish woman named Iona Atkins who is battling Turner Syndrome and a craniopharyngioma at the same time. Read more: 

UCLA Endocrinologist Discusses Medication for Hypogonadism

The Urology Times featured an interview with UCLA endocrinologist Ronald S. Swerdloff, MD, MACP, discussing the approved indication and efficacy of an oral testosterone capsule called Jatenzo (testosterone undecanoate). On the same page is a report about another medication called Kyzatrex. The FDA has accepted a new drug application (NDA) for SOV2012-F1 (Kyzatrex), an oral testosterone undecanoate soft gelatin capsule that is intended to treat adult men with primary or secondary hypogonadism

Cushing’s Drug Reports Positive Results at ENDO 2021

At the Endocrine Society’s annual meeting, ENDO 2021 (held virtually this year) Recordati Rare Diseases reported positive phase III LINC 4 study result for the Cushing’s drug Isturisa® (osilodrostat). The findings indicate that Isturisa “provides rapid and sustained normalization of mean urinary free cortisol levels in the majority of patients.” Read more in BusinessWire:

Warning About Nasal Swab Tests for Post-Surgical Pituitary Patients

An article in HealthDay highlights a study that found that post-surgical pituitary patients and those with sinus issues should be warned against using the nasal swab COVID tests. It also finds that patients may have difficulty finding this information in online post-surgical instructions. Read more:

Misdiagnosis Leads Acromegaly Patient to Pituitary Apoplexy

A story in explores the 15-year medical journey of a woman diagnosed with a tumor on her adrenal gland, then acromegaly, then pituitary apoplexy. Read more:   

Study Finds Triple Risk of Death With Endogenous Cushing’s

A study released at ENDO found that people with endogenous Cushing’s Syndrome have 3 times higher death rates, mostly due to infection and cardiovascular disease.



April 2021 Medical Corner


 Reducing Nelson’s Syndrome in Cushing’s Patients

jason sheehanThis month the PNA Medical Corner spotlights an article co-authored by PNA member Dr. Jason Sheehan of the University of Virginia at Charlottesville. The study finds that refractory Cushing’s disease patients who undergo stereotactic radiosurgery before having a bilateral adrenalectomy have a lower risk of Nelson’s syndrome.
Acta Neurochir (Wien)
2021 Mar 24.
doi: 10.1007/s00701-021-04823-1. Online ahead of print.

Stereotactic radiosurgery before bilateral adrenalectomy is associated with lowered risk of Nelson's syndrome in refractory Cushing's disease patients

Adomas Bunevicius 1, Karen Lavezzo 1, Philip W Smith 2, Mary Lee Vance 3, Jason Sheehan 4
Affiliations expand

PMID: 33759014 DOI: 10.1007/s00701-021-04823-1


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PNA Spotlight: Dr. Brian Williams


brian williamsThis month the PNA Spotlight focuses on Dr. Brian Williams, an Assistant Professor in the Department of Neurosurgery at the University of Louisville School of Medicine in Louisville, KY. He started his education with a B.A. in Biology from Johns Hopkins University in Baltimore, MD. He earned his M.D. at Baylor College of Medicine in Houston, TX. He then completed in internship in surgery and a residency in neurosurgery at the University of Virginia in Charlottesville, VA. He then progressed to a fellowship in skull base and cerebrovascular surgery at Auckland City Hospital in Auckland, New Zealand; and a third fellowship in neurological oncology at MD Anderson Cancer Center in Houston, TX. Dr. Williams answered a series of questions from PNA editors. His responses follow.

 What inspired you to choose your career path?

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March 2021 Research Articles


COVID & the Pituitary

 Pituitary apoplexy in the setting of COVID-19 infection: A case report.

Transcranial approach as surgical treatment for giant pituitary adenoma during COVID 19 pandemic - What can we learn?: A case report.

Insights into the possible impact of COVID-19 on the endocrine system.

 Pituitary Tumors

Clinical profiles of silent corticotroph adenomas compared with silent gonadotroph adenomas after adopting the 2017 WHO pituitary classification system.

Do Anxiety and Mood Vary among Disparate Sleep Profiles in Youth with Craniopharyngioma? A Latent Profile Analysis.

The Pangenomic Classification of Pituitary Neuroendocrine Tumors: Quality Histopathology is Required for Accurate Translational Research.

Editor’s note: Drs. Ezza, Asa and Yamada are longtime members of the PNA.

Non-Functional Pituitary Carcinoma Arising from a Recurrent Null Cell Type Pituitary Adenoma: A Case Report and Review of the Literature.

Clinical profiles of silent corticotroph adenomas compared with silent gonadotroph adenomas after adopting the 2017 WHO pituitary classification system.

Pituitary Surgery

Endoscopic endonasal resection of coexisting pituitary adenoma and meningioma:two cases report and literature review.

Assessment of Available Online Information About Nasopharyngeal Swab Testing in Patient Instructions for Sinus and Pituitary Surgery.

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  • April


Continuing Education Program

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If you are a nurse or medical professional, register for PNA CEU Membership and  earn CEU credits to learn about the symptoms, diagnosis and treatment options for patients with pituitary disorders. Help PNA reduce the time it takes for patients to get an accurate diagnosis.

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