That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.
A group of academic institutions and treatment centers cooperating to perform clinical research and clinical trials.
Central Nervous System.
Childhood onset: adult patients with growth hormone deficiency from childhood.
An instrument which allows visualization of the inside of the colon.
Procedure to examine the colon and rectal tissues by means of an instrument known as a colonoscope.
Existing before or at birth.
21-hydroxylase deficiency (also known as congenital adrenal hyperplasia)
Substances used in radiography that allow visualization of certain tissues.
Surgery performed on the skull where pieces of bone are removed to gain access to the brain, and the bone pieces are not replaced.
Craniopharyngiomas are intracranial tumors that are typically both cystic and solid in structure. They occur most commonly in childhood and adolescence and in later adult life after age 50 years. They account for 2-4% of primary brain tumors.
Surgery performed on the skull where a portion of bone is removed to gain access to the brain, and the bone is put back in its place.
Corticotropin releasing hormone.
A moderately severe chronic inflammation of the intestine, especially of the small intestine, of unknown cause, involving the obstruction of the lower part of the small bowel and less frequently other parts of the gastrointestinal tract. It is characterized by patchy deep ulcers that may cause abnormal passages within the bowel, and narrowing and thickening of the bowel. Symptoms include fever, diarrhea, cramping abdominal pain, and weight loss.