Have you had your hormones checked lately?

PNA Spotlight: Dr. William Couldwell

This month the PNA Spotlight focuses on William Couldwell, MD, PhD, who serves as Professor and Chair of the Department of Neurosurgery at the University of Utah. He is also a member of the PNA’s Scientific Advisory Panel. He studied at the University of British Columbia in Vancouver and at Dalhousie University in Halifax, Nova Scotia, majoring in physical chemistry and biology. Dr. Couldwell attended medical school at McGill University in Montreal. He did internship in surgery at the University of Southern California and completed a neurosurgical residency there in 1989. He served as a research fellow in neuroimmunology at the Montreal Neurological Institute and Hospital and research fellow in the neurosurgical service in Lausanne, Switzerland. He returned to U-S-C as an assistant professor of neurological surgery in 1991, where he stayed for four years. Later he became professor and chairman of the Department of Neurological Surgery at New York Medical College, as well as program director of neurosurgical residency in 1997. In 2001 he became professor and chairman of the Department of Neurosurgery at the University of Utah. Dr. Couldwell was kind enough to answer some questions from the PNA. His answers follow

Please find attached the information about two clinical trials available at WCM. These trials have a novel, selective cortisol receptor blocker for the treatment of ectopic, pituitary, and adrenal Cushing syndrome with overt hypercortisolism (GRACE study). As well as a milder adrenal Cushing SD, where just 1mg Dex test needs to be abnormal (GRADIENT study).

These are phase 3 trials. Also, we have the extension phase for GRACE and are working on getting to our site the extension for GRADIENT study. This will permit patients to utilize the drug beyond the clinical trial, till it becomes available in the market.

PNA Gratefully Acknowleges our Supporters

Crinetics is a valuable member of the PNA.

Corcept Therapeutics has provided a generous grant to support the PNA educational efforts.

Xeris Biopharma has provided a generous grant to support the PNA’s educational program.

Pfizer has provided a generous grant to support the PNA’s Educational Webinar program.

Amryt Pharma is a valued member of the PNA.

Recordati is a valued member of the PNA..

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Mission Statement

To support, pursue, encourage, promote and where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

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