The greatest of follies is to sacrifice health for any other kind of happiness.

-Arthur Schopenhauer

 

PNA Spotlight: Dr. Adriana G. Ioachimescu

This month the PNA Spotlight focuses on Adriana G. Ioachimescu, MD, PhD, FACE Professor of Medicine (Division of Endocrinology and Molecular Medicine) and Neurosurgery at the Medical College of Wisconsin, a lifetime professional member of the PNA.
Dr. Ioachimescu was a Professor of Medicine in Endocrinology and Neurosurgery at the Emory University School of Medicine. Dr. Ioachimescu was also co-director and co-founder of the Emory Neuroendocrine Pituitary Center and a consulting editor at Endocrinology and Metabolism Clinics. Previously she worked at Carol Davila University in Bucharest, Romania, and at the Cleveland Clinic.

Dr. Ioachimescu was born in Bucharest, Romania and earned her PhD in Neuroendocrinology from Carol Davila University of Medicine. She completed an internship in internal medicine at Danbury Hospital and then a fellowship in Endocrinology at the Cleveland Clinic. She did residencies in internal medicine at Carol Davila University, Yale University and the Cleveland Clinic.

Dr. Ioachimescu was kind enough to respond to a few questions from the PNA:

PNA Medical Corner: Machine Learning and Pituitary Surgery

An article co-authored by multiple members of the PNA (Including Drs. Samson, Chaichana, and Quinones-Hinojosa) looks at the role of machine learning in forecasting outcomes of pituitary surgery. They conclude that it is not ready yet as no model achieved clinical applicability.

https://pubmed.ncbi.nlm.nih.gov/36979305/

Abstract

Background: The complex nature and heterogeneity involving pituitary surgery results have increased interest in machine learning (ML) applications for prediction of outcomes over the last decade. This study aims to systematically review the characteristics of ML models involving pituitary surgery outcome prediction and assess their reporting quality.

Methods: We searched the PubMed, Scopus, and Web of Knowledge databases for publications on the use of ML to predict pituitary surgery outcomes.

Featured News and Updates

News Articles May 2024

Does a form of dwarfism improve cardiovascular risk?

A study in the Journal Med looks at the longevity of people with Laron’s Syndrome, who have low-growth hormone signaling that causes a form of dwarfism but may also confer lower risk of cancer and heart disease. Read more in the Daily Mail: https://tinyurl.com/5cdmafaj or consult the original study: https://tinyurl.com/2pvzzbev

Case study: Surgical Treatment of Pituitary Macroadenoma​s

A study published on Cureus.com looks at the case of a 48-year old woman with a pituitary macroadenoma. Surgeons removed the tumor but she suffered post-operative complications that required extensive management. They conclude that this type of surgery is complex and requires individualized care.

Acromegalic receives special-made shoes​

An article on Fox5dc.com features the story of an acromegaly patient in Venezuela who holds the record for the world’s biggest feet, according to the Guinness Book of World records. The man, named Jeison Rodriguez Hernandez, has size 26 feet and gets his shoes special-made a company in Germany. Read more: https://www.fox5dc.com/news/man-with-worlds-largest-feet-receives-new-custom-shoes

Study: Female Cushing’s patients develop more new diseases than men after treatment

An article in Cushing’s Disease news looks at a study published in the journal Endocrinology, Diabetes & Metabolism. Researchers found that women were more likely to develop additional diseases than men, when in remission after treatment for Cushing’s syndrome. Read more: https://cushingsdiseasenews.com/news/more-new-disorders-women-than-men-after-cushings-remission-study/

Research Articles

May 2024 Research Articles

Pituitary Surgery

The effect of preoperative TSH levels on perioperative complications in patients undergoing pituitary surgery.

Report on Pseudoaneurysm Caused by Injury of Internal Carotid Artery During Endoscopic Pituitary Surgery and Rebleeding After Treatment With Willis Covered Stent.

Efficacy of the Craniopharyngioma Resection via Expanded Endoscopic Endonasal Transsphenoidal Approach in the Treatment of Complex Craniopharyngioma and Its Effect on Pituitary Function and Complications of Patients.

Vascular complications in craniopharyngioma-resected paediatric patients: a single-center experience.

Cushing’s

Improvement in clinical features of hypercortisolism during osilodrostat treatment: findings from the Phase III LINC 3 trial in Cushing’s disease. 

Hormonal Health

Hypogonadotropic Hypogonadism. 

Long term pituitary function, functional- and patient reported outcomes in severe acquired brain injury. 
 

Panax ginseng Ameliorates Pituitary-Ovarian Dysfunction Induced by Radiofrequency Electromagnetic Radiation from Cell Phones via Upregulation of the CREM Signaling Pathway. 

Diagnosis and treatment of hypogonadism in men seeking to preserve fertility – what are the options? 

Pituitary Tumors

Rathke’s Cleft Cyst and Craniopharyngioma: A Continuum of the Same Spectrum? Insights from an Interesting Case and Previous Literature. 

Targeted therapy in BRAF mutated aggressive papillary craniopharyngioma: a case report and overview of the literature. 

Disulfiram mediated anti-tumour effect in pituitary neuroendocrine tumours by inducing cuproptosis. 

A long-term prognosis study of human USP8-mutated ACTH-secreting pituitary neuroendocrine tumours. 

Immune landscape and progress in immunotherapy for pituitary neuroendocrine tumors.

 

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Support the PNA  

Support the PNA while you shop! Amazon Smile and Goodshop make donations to non profit organizations based on purchases. Click on the images below for information on how you can select the PNA as your charity and earn money for the PNA on all your online purchases.

Visit our website www.pituitary.org

Join the PNA

Downloadable Pituitary Brochures

Our print quality brochures are now available for download.

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