The winners in life treat their body as if it were a magnificent spacecraft that gives them the finest transportation and endurance for their lives.

-Denis Waitley

 

PNA Spotlight: Dr. William Couldwell

This month the PNA Spotlight focuses on William Couldwell, MD, PhD, who serves as Professor and Chair of the Department of Neurosurgery at the University of Utah. He is also a member of the PNA’s Scientific Advisory Panel. He studied at the University of British Columbia in Vancouver and at Dalhousie University in Halifax, Nova Scotia, majoring in physical chemistry and biology. Dr. Couldwell attended medical school at McGill University in Montreal. He did internship in surgery at the University of Southern California and completed a neurosurgical residency there in 1989. He served as a research fellow in neuroimmunology at the Montreal Neurological Institute and Hospital and research fellow in the neurosurgical service in Lausanne, Switzerland. He returned to U-S-C as an assistant professor of neurological surgery in 1991, where he stayed for four years. Later he became professor and chairman of the Department of Neurological Surgery at New York Medical College, as well as program director of neurosurgical residency in 1997. In 2001 he became professor and chairman of the Department of Neurosurgery at the University of Utah. Dr. Couldwell was kind enough to answer some questions from the PNA. His answers follow.

PNA Medical Corner: Fascia Lata in Reconstructive Neurosurgery

This month the PNA Medical Corner showcases an article co-authored by a member of the PNA, Dr. Varun Kshettry of the Cleveland Clinic. The study concludes that the use of fascia lata in challenging cases of skull base reconstruction is highly effective with few side effects for cases of craniopharyngioma, meningioma and more.

https://pubmed.ncbi.nlm.nih.gov/37081750/

Abstract

Background: Multiple methods exist for skull base reconstruction of defects created by expanded endonasal approaches. While the nasoseptal flap (NSF) has been well established as the workhorse of mucosal reconstruction in complex skull base defects in multi-layered closures, a variety of options exist for the inner layer of multilayer reconstruction, including fascia lata (FL).

Objective: To present our experience and outcomes in utilizing FL in multiple ways to reconstruct a wide variety of complex skull base defects

Featured News and Updates

News Articles October 2026

Pituitary story: teen battles craniopharyngioma

A story in the Yakima Herald spotlights the case of a high school student from Washington State who underwent surgery for a craniopharyngioma near his pituitary gland. Read more:

https://www.yakimaherald.com/news/local/education/highland-student-overcomes-rare-tumor-to-return-to-schools-band/article_f94abec5-7492-4517-9edc-5739023e3982.amp.html

Germ cell tumors masquerading as pituitary inflammation

A new study from China looks at germ cell tumors in adults and concludes that they can often be mistaken for pituitary inflammation. Read more: https://bioengineer.org/rare-brain-germ-cell-tumors-in-adults-often-masquerade-as-pituitary-inflammation-study-finds/

Pituitary story: 82-year-old undergoes pituitary neurosurgery

A hospital in Srinagar, India, reports on a high-risk surgery on an 82-year-old female patient to remove a pituitary macroadenoma. Read more: https://kashmirconvener.com/82-year-old-woman-undergoes-high-risk-pituitary-tumour-surgery-at-paras-srinagar/

 

Child in Ukraine receives donation of pituitary medicine

The nonprofit Direct Relief  reports on the case of a 12-year-old boy in Ukraine with pituitary dwarfism who has received growth hormone medications, thanks to charitable donations. The Russian invasion of Ukraine has severely disrupted medical supplies in that country.  Read more: https://www.directrelief.org/2026/09/ukraine-war-children-growth-hormone-donations/

Case study: Craniopharyngioma linked to spontaneous singing

A story in Medical Daily.com looks at the case of a woman in Poland with a craniopharyngioma whose symptoms included a spontaneous desire to sing religious songs. The symptom subsided after surgical intervention, but then returned.

https://www.medicaldaily.com/brain-lesions-spirituality-circuit-religious-singing-tumor-479227

Research Articles

Research Articles October 2026

Pituitary Tumors

Emerging insights into the pathophysiology of pituitary tumour microenvironment.

Fuentes-Fayos AC, Gil-Duque I, De la Rosa-Herencia AS, Sarmento-Cabral A, Flores-Martínez Á, Cano DA, Martínez-Fuentes AJ, Luque RM.Endocr Relat Cancer. 2026 Aug 26:ERC-26-0262. doi: 10.1530/ERC-26-0262. Online ahead of print.

 

Imaging

Brain Tumor Classification from MRI Using Colormap-Based Vision Transformers on the BRISC2025 Dataset.

Ahmed F.J Imaging Inform Med. 2026 Aug 28. doi: 10.1007/s10278-026-02221-6. Online ahead of print.PMID: 42665755

 

Magnetic resonance elastography of brain tumors.

Koyuncu N, Uca YO, Sack I.Z Med Phys. 2026 Aug 28:S0939-3889(26)00093-0. doi: 10.1016/j.zemedi.2026.08.001. Online ahead of print.

 

Pituitary Surgery

Endoscopic endonasal transcavernous surgery for knosp grade 3-4 growth hormone-secreting pituitary neuroendocrine tumors: surgical outcomes and predictors of biochemical remission.

Tian L, Liu M, Luo M, Zhou C, Gu J, Zeng J, Shen Q, Tong Z, Jiang Y, Luo B, Lin J, Sheng Z, Peng Y.Neurosurg Rev. 2026 Aug 28;49(1):542. doi: 10.1007/s10143-026-04467-8.

 

ERAS Protocol Elements and Neurosurgery-Specific Considerations: A Narrative Review.

Domi R, Saxena S, Berger-Estilita J, Biasucci DG, Meco BC, Lilaj K, Huti G, Matot I, Rubulotta F, Camilleri Podesta AM.Turk J Anaesthesiol Reanim. 2026 Aug 28;54(4):248-261. doi: 10.4274/TJAR.2026.2606.

 

Refining the posterior compartment of the cavernous sinus: a detailed reappraisal of surgical anatomy and techniques for invasive pituitary adenoma resection.

Xu Y, Uchida T, Burgos-Sosa E, Alvarez AS, Rinaldi M, Nakase T, Banu MA, Agostini L, Xiao L, Vigo V, Nisson PL, Menaker SA, Cohen-Gadol AA, Fernandez-Miranda JC.J Neurosurg. 2026 Aug 28:1-13. doi: 10.3171/2026.4.JNS252898. Online ahead of print.

Editor’s note: Dr. Fernandez-Miranda is a member of the PNA.


SurgAnt-ViVQA: learning to anticipate surgical events through GRU-driven temporal cross-attention.

Dhake SC, Huang J, He R, Khan DZ, Mazomenos EB, Bano S, Marcus HJ, Stoyanov D, Clarkson MJ, Hoque MI.Int J Comput Assist Radiol Surg. 2026 Aug 26. doi: 10.1007/s11548-026-03784-z. Online ahead of print.

 

Probable Postsurgical Parsonage-Turner Syndrome Following Endoscopic Endonasal Pituitary Surgery: A Diagnostic Challenge Case Report: Illustrative Case.

Javidialsaadi M, Obillo A, Germanwala A, Ghannad AS, Jani RH, Ng I, Prabhu VC, Patel CR, Germanwala AV.Case Rep Neurol Med. 2026 Aug 25;2026:1964813. doi: 10.1155/crnm/1964813. eCollection 2026.

 

Extent of resection and craniopharyngioma recurrence: a volumetric analysis.

Sarkar S, Vijayaraghavan S, Thakar S, Aryan S.J Neurooncol. 2026 Aug 29;179(2):65. doi: 10.1007/s11060-026-05770-6.

 

Analysis of the factors affecting the quality of life in patients with pituitary adenomas before and after endoscopic transsphenoidal surgery.

Liang W, Xia X, Fan K, Yang T, Cheng J, Zhu X, Li Y, Wang J, Ma Y, Yang Y.Front Endocrinol (Lausanne). 2026 Aug 13;17:1796777. doi: 10.3389/fendo.2026.1796777. eCollection 2026.

 

Acromegaly

Acromegaly Discovered After Head Trauma: Multivessel Coronary Disease and Postoperative Meningitis Complicating a Pituitary Macroadenoma.

Rockwell S, Boley JS, Pulido N, Safa M, Chertman LS.Cureus. 2026 Jul 28;18(7):e113532. doi: 10.7759/cureus.113532. eCollection 2026 Jul.

 

Acromegaly and colorectal cancer risk: emerging roles of the gut microbiota.

Grifoni GFA, Favero V, Cozzi RC, Chiodini I.Front Endocrinol (Lausanne). 2026 Aug 13;17:1820034. doi: 10.3389/fendo.2026.1820034. eCollection 2026.


Delayed diagnosis of acromegaly when lower facial features were obscured by masks during the COVID-19 pandemic.

Sakaue TA, Mukai K, Kajimoto Y, Obata Y, Takahara M, Shimomura I.JCEM Case Rep. 2026 Aug 28;4(9):luag163. doi: 10.1210/jcemcr/luag163. eCollection 2026 Sep.PMID: 42666735 

 

Hormonal Health

Emerging peptide and neuroendocrine strategies for TRT-induced reproductive suppression and functional male hypogonadism: a narrative review.

Cretu AM, Kamar AAM, Ciobica A, Puia D, Doroftei M, Doroftei B.Front Reprod Health. 2026 Aug 14;8:1914709. doi: 10.3389/frph.2026.1914709. eCollection 2026.

 

 

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