A metabolic disease in which carbohydrate utilization is reduced and that of lipid and protein enhanced; it is caused by an absolute or relative deficiency of insulin and is characterized, in more severe cases, by chronic hyperglycemia, glycosuria, water and electrolyte loss, ketoacidosis, and coma; long-term complications include development of disorders of the nervous system, eyes and kidneys; generalized degenerative changes in large and small blood vessels, and increased susceptibility to infection.
Two types of a highly variable disorder in which abnormalities in the ability to make and/or use the hormone insulin interfere with the process of turning dietary carbohydrates into glucose, the body’s fuel. Type I is known as insulin dependent diabetes mellitus, and type II is known as non-insulin dependent diabetes mellitus.