Acromegaly is an insidious disorder, due to chronic hypersecretion of growth hormone (GH) occurring in adulthood. GH hypersecretion prior to epiphyseal fusion results in gigantism. Elevated GH and/or insulin-like growth factor-1 (IGF-1) levels affect multiple organ...
Andrew E. Sloan, Keith A. Black, and Donald P. Becker The treatment of sellar lesions is one of the more challenging and satisfying aspects of skull base surgery. The wide variety of lesions that occur in this region and the complexity of their treatment necessitates...
Donald P. Becker, M.D. Indications Figure 1: Patient position for transsphenoidal approach. The transsphenoidal approach is the procedure of choice for the removal of tumors of the sella that are still largely confined to this space. It is also indicated for removal...
Martin N. Montoro, MD, and Jorge H. Mestman, MD Changes In The Normal Anterior Pituitary Gland During Pregnancy Anatomic and functional changes take place in the pituitary gland during pregnancy that have to be taken into consideration to properly evaluate its...
Predictors of Outcome and Long-Term Results The February, l999 issue of the journal Neurosurgery contains a report by Tyrrell and colleagues from the University of California in San Francisco (UCSF) in which early outcomes and long-term results are analyzed in a large...
