Man needs difficulties; they are necessary for health.

-Carl Jung

PNA Spotlight: Dr. Yuval Eisenberg

This month the PNA Spotlight shines on Dr. Yuval Eisenberg.  Dr. Eisenberg graduated from the Rush Medical College of Rush University Medical Center in 2009. He works in Chicago, IL and 2 other locations and specializes in Endocrinology, Diabetes & Metabolism and Internal Medicine. Dr. Eisenberg is affiliated with University Of Illinois Hospital Health & Science Center.  He was kind enough to answer some of our questions:

• What inspired you to choose your career path?

PNA Medical Corner: The Size of Pituitary Microadenomas .

This month the PNA Medical Corner showcases a study co-authored by Drs. Edward Laws and Ursula Kaiser, both longtime members of the PNA. The study looks at the size of microadenomas over time. It concludes that two-thirds of microadenomas studied either stayed the same or shrank over time, and therefore that “less frequent pituitary MRI surveillance for patients with incidental pituitary microadenomas may be safe.”

https://www.acpjournals.org/doi/10.7326/M22-1728

Abstract

Featured News and Updates

News Articles August 2026

Secretary of Defense concerned about low testosterone in the military

Secretary of Defense Pete Hegseth is mandating testing of male troops over age 30 for low testosterone and will offer testosterone replacement therapy. Many endocrinologists say this approach is problematic. Read more: https://arstechnica.com/health/2026/07/hegseth-wants-a-high-t-military-doctors-call-it-a-clinical-minefield/

The Endocrine Society issue statement in the wake of Hegseth’s announcement:

https://www.endocrine.org/news-and-advocacy/news-room/2026/statement-on-testosterone-replacement-therapy

Pituitary story: Lionel Messi

Soccer mega-star Lionel Messi was diagnosed with growth hormone deficiency as a child. Read more: https://www.msn.com/en-in/health/other/lionel-messi-overcame-growth-hormone-deficiency-as-a-child-a-condition-that-almost-derailed-his-football-dream/ar-AA280JJc

Vision issues in acromegaly

PNA member Dr. Maria Fleseriu is featured in an article in EverydayHealth.com about how acromegaly can affect a patient’s eyesight. Read more: https://www.everydayhealth.com/hormones-metabolic-disorders/how-acromegaly-can-affect-your-eyesight/

Delayed diagnosis of Cushing’s in Japanese children

An article in Cushing’s Disease News looks at a study that found Japanese children often face delays in diagnosis of Cushing’s disease, but many are successfully treated with surgery. Read more: https://cushingsdiseasenews.com/news/japanese-children-face-long-delays-cushings-disease-diagnosis/

Pituitary story: Idaho teen battles germinoma near pituitary gland

Delayed puberty and growth, combined with diabetes insipidus, led doctors to diagnose a 16-year-old boy from Idaho with a germ cell tumor near his pituitary gland. Read more: https://www.fredhutch.org/en/news/blog/2026/07/college-bound-16-year-old-didnt-let-germinoma-get-him-down.html

Pituitary surgery story: Transsphenoidal surgery at Walter Reed

A story in the Times of India highlights the work of an Indian American pituitary surgeon at Walter Reed National Military Medical Center in Bethesda, Maryland: Major Jagatkumar “J.” Patel, and his colleague Army neurosurgeon Lt. Col. Charles Miller.  Read more: https://timesofindia.indiatimes.com/health/indian-american-army-surgeon-removes-golf-ball-sized-brain-tumour-through-a-patients-nose-avoiding-open-skull-surgery/amp_articleshow/132781973.cms

Experts play down the idea of “male menopause”

An article in the Kansas City Star explains that men do not experience a sharp drop-off in hormones in the same way women do; the process is more gradual. Read more: https://www.kansascity.com/living/article316673842.html

The same reporter looks at testosterone replacement therapy in an article in the Miami Herald: https://www.miamiherald.com/living/article316675898.html

Research Articles

Research Articles August 2026

Pituitary tumors

Predicting hormonal deterioration following transsphenoidal surgery for non-functioning pituitary adenomas: A systematic review and meta-analysis.

Ameen D, ElSabban Y, Kalaitzoglou D, Shapey J, Barazi S, Thomas N, Aylwin S, Maratos E.Endocrine. 2026 Aug 1;91(1):243. doi: 10.1007/s12020-026-04712-6.

 

Effect of sellar and parasellar brain tumors on retinal thickness and visual fields: A cross-sectional comparative study.

Kasireddy HD, Sahu V, Sharma A, Kumar A, Shrivastava S.Indian J Ophthalmol. 2026 Aug 1;74(8):1185-1190. doi: 10.4103/IJO.IJO_215_26. Epub 2026 Jul 31.


Case report of two growth hormone-secreting invasive pituitary adenomas and literature review.

Zhou J, Wen J, Leng H, Yi J.Arch Med Sci. 2026 Jun 23;22(3):1926-1931. doi: 10.5114/aoms/224312. eCollection 2026.


Statistical Geometric Morphometric Shape Analysis of Ventricular Shape Changes in Giant Pituitary Adenomas Invading the Third Ventricle.

Altunyuva O, Balcin N, Ocakoglu G, Taskapilioglu MO, Yilmazlar S.Turk Neurosurg. 2026;36(4):509-516. doi: 10.5137/1019-5149.JTN.49331-25.2.

 

Personalized prediction of local control after stereotactic radiosurgery for craniopharyngioma: a multicenter machine learning survival model.

Reyes JS, Hadjipanayis CG, Bernstein K, Speckter H, Gonzalez I, Chytka T, Liscak R, Bowden GN, Sumi T, Narita K, Kano H, Martínez-Moreno N, Martínez-Álvarez R, Picozzi P, Franzini A, Tripathi M, Rai A, Kumar N, Douri K, Mathieu D, Dono A, Amezquita-Contreras C, Blanco AI, Esquenazi Y, Tos SM, Mantziaris G, Peker S, Samanci Y, Duzkalir AH, Meng Y, Sheehan JP, Kondziolka D, Lunsford LD, Niranjan A.J Neurooncol. 2026 Jul 31;179(1):22. doi: 10.1007/s11060-026-05736-8.

Editor’s note: Dr. Sheehan is a member of the PNA.

 

Cushing’s

Annexin A1 as a diagnostic biomarker for cyclic Cushing disease.

Rao Z, Wu L, Jiang L, Su T, Cao Y, Lin S, He X, Ye Y, Ning G, Wang W, Zhang C.iScience. 2026 Jul 22;29(8):116907. doi: 10.1016/j.isci.2026.116907. eCollection 2026 Aug 21.

 

MRI predictive value for adenoma detection in Cushing’s disease and reader dependence: a multi-observer study.

Constanthin PE, Ferrière A, Sanchez-Gallardo F, Nunes ML, Berge J, Engelhardt J.J Neurosurg. 2026 Jul 31:1-9. doi: 10.3171/2026.2.JNS252331. Online ahead of print.

 


Baseline biochemical evaluation for etiologic differentiation in ACTH-dependent Cushing’s syndrome: machine learning and composite score analysis in a multicenter cohort of 566 patients.

Detomas M, Prada Salcedo JP, Altieri B, Stüfchen I, Nasi-Kordhishti I, Wolfsberger S, Losa M, Quinkler M, Kimpel O, Vila G, Honegger JB, Rubinstein G, Fassnacht M, Deutschbein T.Eur J Endocrinol. 2026 Jul 31:lvag141. doi: 10.1093/ejendo/lvag141. Online ahead of print.

 

Acromegaly

 

Assessment of nurses’ knowledge and awareness of acromegaly in a high-volume tertiary center: a cross-sectional study.

Genc B, Polat SB, Koc A, Ersoy R.Pituitary. 2026 Jul 31;29(4):136. doi: 10.1007/s11102-026-01737-y.

 

Hormonal health

 

Pituitary Apoplexy Without Chiasmal Compression Presenting With Radiographic Oculomotor Nerve Compression in a Prolactinoma: A Case Report.

Holz EA, Imran M, Reyes N, Izquierdo-Pretel G.Cureus. 2026 Jun 30;18(6):e111830. doi: 10.7759/cureus.111830. eCollection 2026 Jun.

 

 

Progressive Cerebellar Dysfunction, Pituitary Insufficiency, and Severe Skeletal Fragility in Adult Survivorship of Childhood Multisystem Langerhans Cell Histiocytosis: A Case Report.

Alnahar S, Senjab A, Gharib S, Gharib Z, Hadid L.Clin Case Rep. 2026 Jul 29;14(8):e73261. doi: 10.1002/ccr3.73261. eCollection 2026 Aug.


A Novel LHX3 Variant Associated With Combined Pituitary Hormone Deficiency in an Indian Kindred.

Palaniappan S, Sridhar S, Thasarathan S, Shanmugam D, Dutta P.Cureus. 2026 Jun 29;18(6):e111778. doi: 10.7759/cureus.111778. eCollection 2026 Jun.

 

 

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